Men
tend to store fat in the abdominal area, but don’t usually have
much in the way of hips or thighs. Women, on the other hand, are more
often pear-shaped, storing more fat on their hips and thighs than in
the belly.
Why
are women and men shaped differently?
The
research led by Steven Smith, director of the Florida Hospital –
Sanford-Burnham Translational Research Institute for Metabolism and
Diabetes, found that the genes operating in a person’s thigh fat
are hugely different from those in his or her belly fat.
Smith
and colleagues first took fat samples from men and women. Then they
compared the genes most active in belly fat to those most active in
thigh fat, the Journal of Clinical Endocrinology and Metabolism
reports.
For
men, 125 genes are expressed differently in the belly than in the
thighs. For women, it’s 218 genes (most unique to women, but 59
genes are the same as those that varied in male fat).
That’s
because belly fat is tied to higher risks of heart disease and
diabetes. On the other hand, hip and thigh fat don’t seem to play a
special role in these conditions, according to a Florida Hospital
statement.
Smith
and colleagues help explain this discrepancy by determining how belly
and thigh fat differ genetically. This research might shift common
thinking about fat – rather than focusing on how to banish belly
fat, perhaps we need to tip the balance in favour of heart-friendly
fat in the lower body.
-
Agencies
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